Original Article

Potential Hepatoprotective Effects of Irbesartan, an Accessible Angiotensin II Receptor Blocker, Against Cisplatin-Induced Liver Injury in a Rat Model
  • Onur ERTUNÇ
  • Yalçın ERZURUMLU
  • Mehtap SAVRAN
  • Deniz ÇATAKLI
  • Eltaf DOĞAN KIRAN
  • Şakir PEKGÖZ
Turk J Pharm Sci 0; 0: 0-0 [e-Pub] DOI: 10.4274/tjps.galenos.2023.90846
Effect of nutrition on drug-induced liver injury: insights from a high-fat diet mouse model
  • Murali Badanthadka
  • Vinitha Dsouza
  • Meghashree Shetty
  • Varsha A.
  • Madhura R.j.
  • Mamatha B.s.
  • Vijayanarayana Kunhikatta
Turk J Pharm Sci 0; 0: 0-0 [e-Pub] DOI: 10.4274/tjps.galenos.2023.23855
Phytochemical and toxicological analysis of an herbal mixture containing Hypericum perforatum and Melissa officinalis
  • Mehran Zamany
  • Faezeh Fatemi
  • Somayeh Farahmand
Turk J Pharm Sci 0; 0: 0-0 [e-Pub] DOI: 10.4274/tjps.galenos.2023.28092
3-(1H-pyrazole-1-yl/1H-1,2,4-triazole-1-yl)-N-propananilide derivatives: Design, Synthesis and Neuroprotectivity Potential Against 6-OHDA Induced Neurotoxicity Model
  • Ayşe Hande Tarıkoğulları Doğan
  • Merve Saylam
  • Sinem Yılmaz
  • Sulunay Parlar
  • Petek Ballar
  • Vildan Alptuzun
Turk J Pharm Sci 0; 0: 0-0 [e-Pub] DOI: 10.4274/tjps.galenos.2024.72365
An In Vitro Study on the Interactions of Pycnogenol® with Cisplatin in Human Cervical Cancer Cells
  • Merve BECİT
  • Sevtap AYDIN
Turk J Pharm Sci 2020; 17: 1-6 DOI: 10.4274/tjps.galenos.2018.97759 PMID:32454754
The Ameliorate Effects of Nerolidol on Thioacetamide-induced Oxidative Damage in Heart and Kidney Tissue
  • Neşe Başak TÜRKMEN
  • Hande YÜCE
  • Aslı TAŞLIDERE
  • Yasemin ŞAHİN
  • Osman ÇİFTÇİ
Turk J Pharm Sci 2022; 19: 1-8 DOI: 10.4274/tjps.galenos.2021.30806 PMID:35227035
Ameliorative Potential of Rosuvastatin on Doxorubicin-induced Cardiotoxicity by Modulating Oxidative Damage in Rats
  • Jayaraman RAJANGAM
  • Navaneetha KRISHNAN S
  • Narahari N PALEI
  • Shvetank BHATT
  • Manas Kumar DAS
  • Saumya DAS
  • Krishnapillai MATHUSOOTHANAN
Turk J Pharm Sci 2022; 19: 28-34 DOI: 10.4274/tjps.galenos.2021.70745 PMID:35227038
Antiplasmodial Activity of the n-Hexane Extract from Pleurotus ostreatus (Jacq. ex. Fr) P. Kumm.
  • Ozadheoghene Eriarie AFIEROHO
  • Xavier Siwe NOUNDOU
  • Chiazor P. ONYIA
  • Osamuyi H. FESTUS
  • Elizabeth C. CHUKWU
  • Olutayo M. ADEDOKUN
  • Michelle ISAACS
  • Heinrich C. HOPPE
  • Rui WM. KRAUSE
  • Kio A. ABO
Turk J Pharm Sci 2019; 16: 37-42 DOI: 10.4274/tjps.18894 PMID:32454693
Fusariotoxin-Induced Toxicity in Mesenchymal Stem Cells and Fibroblasts: A Comparison Between Differentiated and Undifferentiated Cells
  • Inji SHIKHALIYEVA
  • Cenk KIĞ
  • Ömer Yavuz GÖMEÇ
  • Gülruh ALBAYRAK
Turk J Pharm Sci 2024; 21: 62-70 DOI: 10.4274/tjps.galenos.2023.76128 PMID:38529558
Determination of the Phototoxicity Potential of Commercially Available Tattoo Inks Using the 3T3-neutral Red Uptake Phototoxicity Test
  • Elif Gözde UTKU TÜRK
  • Ayse Tarbin JANNUZZI
  • Buket ALPERTUNGA
Turk J Pharm Sci 2022; 19: 70-75 DOI: 10.4274/tjps.galenos.2021.86344 PMID:35227052
Synthesis and Anticancer and Antimicrobial Evaluation of Novel Ether-linked Derivatives of Ornidazole
  • Sevil ŞENKARDEŞ
  • Necla KULABAŞ
  • Özlem BİNGÖL ÖZAKPINAR
  • Sadık KALAYCI
  • Fikrettin ŞAHİN
  • İlkay KÜÇÜKGÜZEL
  • Ş. Güniz KÜÇÜKGÜZEL
Turk J Pharm Sci 2020; 17: 81-93 DOI: 10.4274/tjps.galenos.2018.59389 PMID:32454765
The Nanosuspension Formulations of Daidzein: Preparation and In Vitro Characterization
  • Afife Büşra UĞUR KAPLAN
  • Naile ÖZTÜRK
  • Meltem ÇETİN
  • İmran VURAL
  • Tuba ÖZNÜLÜER ÖZER
Turk J Pharm Sci 2022; 19: 84-92 DOI: 10.4274/tjps.galenos.2021.81905 PMID:35227054
Subchronic Toxicity Assessment of Orally Administered Methanol (70%) Seed Extract of Abrus precatorius L. in Wistar Albino Rats
  • Shazia TABASUM
  • Swati KHARE
  • Kirti JAIN
Turk J Pharm Sci 2019; 16: 88-95 DOI: 10.4274/tjps.87487 PMID:32454701
Assessment of In Vitro Antigenotoxic Effect of Nigella Sativa Oil
  • Murat ZOR
  • Elçin Latife ASLAN
Turk J Pharm Sci 2020; 17: 115-118 DOI: 10.4274/tjps.galenos.2020.09471 PMID:32454769
Protective Role of Diospyros lotus L. in Cisplatin-Induced Cardiotoxicity: Cardiac Damage and Oxidative Stress in Rats
  • Neşe BAŞAK TÜRKMEN
  • Dilan AŞKIN ÖZEK
  • Aslı TAŞLIDERE
  • Osman ÇİFTÇİ
  • Özlem SARAL
  • Cemile Ceren GÜL
Turk J Pharm Sci 2022; 19: 132-137 DOI: 10.4274/tjps.galenos.2021.84555 PMID:35509232
In Vivo Antioxidant Activity of Different Fractions of Indigofera Barberi Against Paracetamol-induced Toxicity in Rats
  • Shaik AMINABEE
  • Atmakuri Lakshmana RAO
  • Maram Chinna ESWARAIAH
Turk J Pharm Sci 2020; 17: 136-140 DOI: 10.4274/tjps.galenos.2018.30306 PMID:32454772
A Combination of Virgin Coconut Oil and Extra Virgin Olive Oil Elicits Superior Protection Against Doxorubicin Cardiotoxicity in Rats
  • Andi Ulfiana UTARI
  • Yulia Yusrini DJABIR
  • Bogie Putra PALINGGI
Turk J Pharm Sci 2022; 19: 138-144 DOI: 10.4274/tjps.galenos.2021.37998 PMID:35509244
Chitosan-Based Microparticle Encapsulated Acinetobacter baumannii Phage Cocktail in Hydrogel Matrix for the Management of Multidrug Resistant Chronic Wound Infection
  • Margaret O. ILOMUANYA
  • Nkechi V ENWURU
  • Emmanuella ADENOKUN
  • ABIGAIL FATUNMBI
  • Adebowale ADELUOLA
  • Cecilia I IGWILO
Turk J Pharm Sci 2022; 19: 187-195 DOI: 10.4274/tjps.galenos.2021.72547 PMID:35510310
Protective Effect of Apis dorsata Honey on Chronic Monosodium Glutamate-Induced Testicular Toxicity in Mus musculus Mice
  • Epy Muhammad LUQMAN
  • Aditya Tri ANANDA
  • Widjiati WIDJIATI
  • Viski Fitri HENDRAWAN
Turk J Pharm Sci 2022; 19: 246-250 DOI: 10.4274/tjps.galenos.2021.30737 PMID:35773997
Cardioprotective Effect of Marsdenia tenacissima and Sansevieria roxburghiana in Doxorubicin-induced Cardiotoxicity in Rats in vivo: The Role of Dresgenin and Lupeol
  • Aparna Ann MATHEW
  • Raju ASIRVATHAM
  • Dawn V TOMY
Turk J Pharm Sci 2021; 18: 271-281 DOI: 10.4274/tjps.galenos.2020.27880 PMID:34157816
An In Vitro Study on the Cytotoxicity and Genotoxicity of Silver Sulfide Quantum Dots Coated with Meso-2,3-dimercaptosuccinic Acid
  • Deniz ÖZKAN VARDAR
  • Sevtap AYDIN
  • İbrahim HOCAOĞLU
  • Havva YAĞCI ACAR
  • Nursen BAŞARAN
Turk J Pharm Sci 2019; 16: 282-291 DOI: 10.4274/tjps.galenos.2018.85619 PMID:32454726
Hepatoprotective Activity of Gentisic Acid on 5-Fluorouracil-induced Hepatotoxicity in Wistar Rats
  • Rohini Revansiddappa PUJARI
  • Deepti Dinesh BANDAWANE
Turk J Pharm Sci 2021; 18: 332-338 DOI: 10.4274/tjps.galenos.2020.95870 PMID:34157823
Phytochemical Constituents, Antioxidant Activity, and Toxicity Assessment of the Seed of Spondias mombin L. (Anacardiaceae)
  • Oyindamola Olajumoke ABIODUN
  • Mesoma Esther NNORUKA
  • Rasidat Olufunke TIJANI
Turk J Pharm Sci 2020; 17: 343-348 DOI: 10.4274/tjps.galenos.2020.38801 PMID:32636713
The Influence of Piperine on the Radioprotective Effect of Curcumin in Irradiated Human Lymphocytes
  • Noora GHELISHLI
  • Arash GHASEMI
  • Seyed Jalal HOSSEINIMEHR
Turk J Pharm Sci 2019; 16: 366-370 DOI: 10.4274/tjps.galenos.2018.50103 PMID:32454737
Comparative In Vitro Assessment of the Methanol Extracts of the Leaf, Stem, and Root Barks of Cnidoscolus aconitifolius on Lung and Breast Cancer Cell Lines
  • Emmanuel Oise OIKPEFAN
  • Buniyamin Adesina AYINDE
  • Azhar MUDASSIR
  • Ahsana Dar FAROOQ
Turk J Pharm Sci 2019; 16: 375-379 DOI: 10.4274/tjps.galenos.2018.19942 PMID:32454739
Phytotoxicity, Toxicity on Brine Shrimp and Insecticidal Effect of Chrysophthalmum gueneri Aytac & Anderb. Growing in Turkey
  • Fatma AYAZ
  • Nurgün KÜÇÜKBOYACI
  • Barış BANİ
  • Bilge ŞENER
  • Muhammad Iqbal CHOUDHARY
Turk J Pharm Sci 2018; 15: 382-385 DOI: 10.4274/tjps.88700 PMID:32454686
Preparation and Characterization of Chitosan and Inclusive Compound-Layered Gold Nanocarrier to Improve the Antiproliferation Effect of Tamoxifen Citrate in Colorectal Adenocarcinoma (Caco-2) and Breast Cancer (MCF-7) Cells
  • Yahia KAHLOUS
  • Vijayaraj Kumar PALANIRAJAN
  • Melbha STARLIN
  • Jeetendra Singh NEGI
  • Shiau-Chuen CHEAH
Turk J Pharm Sci 2022; 19: 391-399 DOI: 10.4274/tjps.galenos.2021.48961 PMID:36047535
Effects of Oleuropein on Epirubicin and Cyclophosphamide Combination Treatment in Rats
  • Metin Deniz KARAKOÇ
  • Selim SEKKİN
Turk J Pharm Sci 2021; 18: 420-429 DOI: 10.4274/tjps.galenos.2020.69008 PMID:34496482
Safety Assessment of Vanillic Acid: Subacute Oral Toxicity Studies in Wistar Rats
  • Anwarbaig Chandbaig MIRZA
  • Shital Sharad PANCHAL
Turk J Pharm Sci 2020; 17: 432-439 DOI: 10.4274/tjps.galenos.2019.92678 PMID:32939140
Cytotoxic, Genotoxic, and Apoptotic Effects of Nickel Oxide Nanoparticles in Intestinal Epithelial Cells
  • Mahmoud ABUDAYYAK
  • Elif GÜZEL
  • Gül ÖZHAN
Turk J Pharm Sci 2020; 17: 446-451 DOI: 10.4274/tjps.galenos.2019.76376 PMID:32939142
Phytochemical Screening and Toxicological Evaluation of Sargassum wightii Greville in Wistar Rats
  • Sathiya RAMU
  • Anita MURALI
  • Anbu JAYARAMAN
Turk J Pharm Sci 2019; 16: 466-475 DOI: 10.4274/tjps.galenos.2018.68442 PMID:32454751
Acetamiprid-induced Cyto- and Genotoxicity in the AR42J Pancreatic Cell Line
  • Mehtap KARA
  • Ezgi ÖZTAŞ
  • Gül ÖZHAN
Turk J Pharm Sci 2020; 17: 474-479 DOI: 10.4274/tjps.galenos.2019.89719 PMID:33177926
Cytotoxic Activity of Sesquiterpenoids Isolated from Endemic Ferula tenuissima Hub.-Mor & Peşmen
  • Fadime AYDOĞAN
  • Şura BAYKAN
  • Bilge DEBELEÇ BÜTÜNER
Turk J Pharm Sci 2019; 16: 476-480 DOI: 10.4274/tjps.galenos.2018.23356 PMID:32454752
Flusilazole Induced Cytotoxicity and Inhibition of Neuronal Growth in Differentiated SH-SY5Y Neuroblastoma Cells by All-Trans-Retinoic Acid (Atra)
  • Elif KARACAOĞLU
Turk J Pharm Sci 2021; 18: 597-603 DOI: 10.4274/tjps.galenos.2021.30676 PMID:34719187
In Vitro Cytotoxicity and Oxidative Stress Evaluation of Valerian (Valeriana officinalis) Methanolic Extract in Hepg2 and Caco2 Cells
  • Mehtap KARA
  • Ecem Dilara ALPARSLAN
  • Ezgi ÖZTAŞ
  • Özlem Nazan ERDOĞAN
Turk J Pharm Sci 2021; 18: 604-608 DOI: 10.4274/tjps.galenos.2021.04903 PMID:34719188
Cytotoxic Effects of Verbascoside on MCF-7 and MDA-MB-231
  • Hülya ŞENOL
  • Pinar TULAY
  • Mahmut Cerkez ERGÖREN
  • Azmi HANOĞLU
  • İhsan ÇALIŞ
  • Gamze MOCAN
Turk J Pharm Sci 2021; 18: 637-644 DOI: 10.4274/tjps.galenos.2021.36599 PMID:34719192
Lentinus squarrosulus Mont. Mushroom: Molecular Identification, In vitro Anti-Diabetic, Anti-Obesity, and Cytotoxicity Assessment
  • Oyindamola Olajumoke ABIODUN
  • Adenike Martha ALEGE
  • Precious Ulomma EZURIKE
  • Abraham NKUMAH
  • Oluwatosin ADELOWO
  • Tolulope Aderinola OKE
Turk J Pharm Sci 2022; 19: 642-648 DOI: 10.4274/tjps.galenos.2021.72798 PMID:36544286
In silico Modeling and Toxicity Profiling of a Set of Quinoline Derivatives as c-MET Inhibitors in the treatment of Human Tumors
  • Gülçin TUĞCU
  • Filiz Esra ÖNEN BAYRAM
  • Hande SİPAHİ
Turk J Pharm Sci 2021; 18: 738-743 DOI: 10.4274/tjps.galenos.2021.54815 PMID:34979735
The Antibacterial, Insecticidal and Nematocidal Activities and Toxicity Studies of Tanacetum falconeri Hook. f.
  • Muhammad ISMAIL
  • Atia KOWSAR
  • Salma JAVED
  • M. Iqbal CHOUDHARY
  • Sher Wali KHAN
  • Qamar ABBAS
  • Yanran TANG
  • Wei WANG
Turk J Pharm Sci 2021; 18: 744-751 DOI: 10.4274/tjps.galenos.2021.63372 PMID:34979736
Investigation of the Genotoxic, Cytotoxic, Apoptotic, and Oxidant Effects of Olive Leaf Extracts on Liver Cancer Cell Lines
  • Muhammed Yunus BEKTAY
  • Eray Metin GÜLER
  • Mustafa GÖKÇE
  • Mustafa Volkan KIZILTAŞ
Turk J Pharm Sci 2021; 18: 781-789 DOI: 10.4274/tjps.galenos.2021.03271 PMID:34979739

Original Article

Cytotoxic Activity of Resveratrol in Different Cell Lines Evaluated by MTT and NRU Assays
  • Hatice Gül ANLAR
  • Merve BACANLI
  • Berkin KUTLUK
  • Arif Ahmet BAŞARAN
  • Nursen BAŞARAN
Turk J Pharm Sci 2016; 13: 27-34
Chemical Composition, Antioxidant and Cytotoxicity Potential of Daniellia oliveri (Rolfe) Hutch. & Dalz.
  • Olubunmi ATOLANI
  • Gabriel A. OLATUNJI
Turk J Pharm Sci 2016; 13: 41-46
A Pilot Study on Effects of Concomitant Usage of Acetaminophen and N-Acetylcysteine to Prevent Possible Acetaminophen Toxicity
  • Sükran ÖZDATLI
  • Hande SIPAHI
  • Mohammad CHAREHSAZ
  • Yüksel BEHZETOGLU
  • Gülengül DUMAN
  • Ahmet AYDIN
Turk J Pharm Sci 2015; 12: 45-52
Development of Cisplatin-loaded Liposome and Evaluation of Transport Properties Through Caco-2 Cell Line
  • Çiğdem YÜCEL
  • Zelihagül DEĞİM
  • Şükran YILMAZ
Turk J Pharm Sci 2016; 13: 69-80
Assessment of Cytotoxicity Profiles of Different Phytochemicals: Comparison of Neutral Red and MTT Assays in Different Cells in Different Time Periods
  • Merve BACANLI
  • Hatice Gül ANLAR
  • A. Ahmet BAŞARAN
  • Nursen BAŞARAN
Turk J Pharm Sci 2017; 14: 95-107 DOI: 10.4274/tjps.07078 PMID:32454600
Effect of Mefenamic Acid on Some of The Base Excision Repair Enzymes Against D-Serine-Induced Neurotoxicity
  • Güliz ARMAĞAN
  • Elvin SEVGİLİ
  • Ezgi TURUNÇ
  • Lütfiye KANIT
  • Ayfer YALÇIN
Turk J Pharm Sci 2016; 13: 103-114
Subcutaneous Toxicity of Agmatine in Rats
  • Tayfun UZBAY
  • Fatma Duygu KAYA YERTUTANOL
  • Ahmet MİDİ
  • Burcu ÇEVRELİ
Turk J Pharm Sci 2017; 14: 127-133 DOI: 10.4274/tjps.85057 PMID:32454603
EVALUATION OF CYTOTOXICITY OF SOME AGENTS AS A SCREENING TEST IN ANTITUMORAL ACTIVITY USING VERO, HE-LA AND HEP-2 CELL CULTURES
  • Berrin Özçelik
  • Taner Karaoglu
  • Ufuk Abbasoglu
Turk J Pharm Sci 2004; 1: 153-163
Synthesis, Cytostatic and Antiviral Activity of Some Ruthenium (II) Complexes
  • Subhas S KARKI
  • Ravikumar TK
  • Arpit KHATIYAR
  • Sreekanth THOTA
  • Sujeet KUMAR
  • Sureshbabu A RAMAREDDY
  • Erik De CLERCQ
  • Jan BALZARINI
Turk J Pharm Sci 2014; 11: 163-174
In Vitro Evaluation of the Toxicity of Cobalt Ferrite Nanoparticles in Kidney Cell
  • Mahmoud ABUDAYYAK
  • Tuba ALTINÇEKİÇ GÜRKAYNAK
  • Gül ÖZHAN
Turk J Pharm Sci 2017; 14: 169-173 DOI: 10.4274/tjps.99609 PMID:32454609
SYNTHESIS AND ANTICANCER ACTIVITY OF SOME BISQUINOXALINE DERIVATIVES
  • İlhan IŞIKDAĞ
  • Yusuf ÖZKAY
  • Zerrin İNCESU
Turk J Pharm Sci 2011; 8: 179-188
Evaluation of the Genotoxic Effects of Patients Undergoing Hyperbaric Oxygen (HBO) Therapy
  • Aylin ÜSTÜNDAĞ
  • Kemal ŞİMŞEK
  • Hakan AY
  • Kadir DÜNDAR
  • Sinan SÜZEN
  • Ahmet AYDIN
  • Yalçın DUYDU
Turk J Pharm Sci 2014; 11: 203-208
SYNTHESIS, CHARACTERIZATION AND CYTOTOXIC ACTIVITY OF SOME Ru(II) COMPLEXES
  • Subhas S. KARKI
  • Arpit KATIYAR
  • Sreekanth THOTA
  • Korlakunta N. JAYAVEERA
  • Eric De CLERCQ
  • Jan BALZARINI
Turk J Pharm Sci 2011; 8: 207-218
Assessment of Cytotoxic Properties of Sinapic Acid In Vitro
  • Hasan HAMEED
  • Sevtap AYDIN
  • Arif Ahmet BAŞARAN
  • Nurşen BAŞARAN
Turk J Pharm Sci 2016; 13: 225-232
Antiinflamatuvar and Antioxidant Properties of Spongosorites halichondriodes, a Marine Sponge
  • Maushmi S KUMAR
  • KK. VIJAYLAXMI
  • Asim K PAL
Turk J Pharm Sci 2014; 11: 285-294
Cytotoxicity Evaluation of Some Phenolic Compounds in V79 Cells
  • Merve BACANLI
  • A. Ahmet BAŞARAN
  • Nursen BAŞARAN
Turk J Pharm Sci 2015; 12: 299-304
Determination of Cytotoxic and Anticandidal Activities of Three Verbascum L. Species from Turkey: V. cheiranthifolium Boiss. var. asperulum (Boiss.) Murb. Monorg., V. pycnostachyum Boiss. & Heldr and V. orgyale Boiss. & Heldr
  • Sevim KÜÇÜK
  • Filiz ÖZDEMİR
  • Gökalp İŞCAN
  • Zerrin İNCESU
Turk J Pharm Sci 2016; 13: 318-322 DOI: 10.4274/tjps.2016.06
HEPATOPROTECTIVE ACTIVITY OF Stevia rebaudiana BERT. LEAVES AGAINST THIOACETAMIDE INDUCED TOXICITY
  • Kuntal DAS
  • Anil Kumar KATHIRIYA
Turk J Pharm Sci 2012; 9: 343-352

Original Articles

Real-Time Cell Analysis of the Cytotoxicity of Origanum acutidens Essential Oil on HT-29 and HeLa Cell Lines
  • Feyza ÖKE ALTUNTAŞ
  • İbrahim DEMİRTAŞ
Turk J Pharm Sci 2017; 14: 29-33 DOI: 10.4274/tjps.40427 PMID:32454591
Cytotoxic Activities of Certain Medicinal Plants on Different Cancer Cell Lines
  • Deniz UĞUR
  • Hatice GÜNEŞ
  • Fatma GÜNEŞ
  • Ramazan MAMMADOV
Turk J Pharm Sci 2017; 14: 222-230 DOI: 10.4274/tjps.80299 PMID:32454617
In Vitro Cytotoxic and Anti-inflammatory Activities of Tanacetum argenteum (Lam.) Willd. subsp. argenteum Extract
  • Gökay ALBAYRAK
  • Ayşe NALBANTSOY
  • Şüra BAYKAN
Turk J Pharm Sci 2017; 14: 231-236 DOI: 10.4274/tjps.42714 PMID:32454618

Review

Pharmacological and Toxicological Properties of Eugenol
  • Solmaz MOHAMMADI NEJAD
  • Hilal ÖZGÜNEŞ
  • Nursen BAŞARAN
Turk J Pharm Sci 2017; 14: 201-206 DOI: 10.4274/tjps.62207 PMID:32454614

Review

Psychoactive Bath Salts and Neurotoxicity Risk
  • Beril ALTUN
  • İsmet ÇOK
Turk J Pharm Sci 2020; 17: 235-241 DOI: 10.4274/tjps.galenos.2018.40820 PMID:32454785